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我们对627例早孕和待产的孕妇,同时对200例早孕孕妇的丈夫检查 HBVM 和 HB-VDNA,HBVDNA 的阳性率分别为16.75%和14.50%。对75例 HBVDNA 阳性的孕妇和23例HBVDNA 阳性的丈夫,取其新生儿脐带血检查 HBVDNA,阳性率分别为62.67%(47/75)和30.43%(7/23),并发现 HBVDNA 阳性合并 HBeAg 阳性时传播率较高,同时发现 HBVM 阴性但 HB-VDNA 阳性的孕妇也可将 HBV 传播给胎儿。因而建议:①产前应对孕妇夫妇双方常规检查 HB-VDNA。②孕前如发现 HBVDNA 阳性合并 HBeAg 阳性者应积极治疗,尽可能待 HBeAg 转阴后再怀孕。③父系传播不容忽视。
We conducted a survey of 627 pregnant women and their expectant mothers. Meanwhile, the positive rates of HBVDNA and HBVDNA in 200 prenatal pregnant women were 16.75% and 14.50%, respectively. The positive rate of HBVDNA in 75 HBVDNA positive pregnant women and 23 HBVDNA positive husbands was 62.67% (47/75) and 30.43% (7/23), respectively. The positive rate of HBVDNA was HBeAg Propagation rate is higher, but also found that HBVM-negative but HB-VDNA-positive pregnant women can also be transmitted to the fetus of HBV. It is suggested: ① prenatal treatment of both pregnant women and husband routine examination of HB-VDNA. ② before pregnancy found HBVDNA positive HBeAg-positive patients should be actively treated, as far as possible HBeAg negative pregnancy before. ③ paternal transmission can not be ignored.