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肺泡的液气界面有一层具有降低表面张力作用的物质,叫作肺表面活性物质(Snrfactant),它为磷脂蛋白复合物,其中主要成分是磷脂酰胆硷(Phosphoti-dylcholine PC),其他为磷脂酰甘油、磷脂酰乙醇胺、鞘磷脂和磷脂酰丝氨酸等。肺表面活性物质对维持肺泡的舒缩,保持不同大小肺泡之间的关系,保持肺泡的干燥起着重要的作用,并且具有抗微生物感染的防御作用。许多疾病与肺表面活性物质有关,例如新生儿呼吸窘迫综合征、成人呼吸窘迫综合征、休克、肺水肿、酸中毒和肺梗塞等。
The alveolar liquid-gas interface has a layer of substance that reduces the surface tension, called the surfactant, which is a phospholipid protein complex in which the major component is Phosphoti-dylcholine PC and the others phospholipids Acyl glycerol, phosphatidylethanolamine, sphingomyelin, phosphatidylserine and the like. Pulmonary surfactant to maintain the alveolar contraction and contraction, to maintain the relationship between different sizes of alveoli, alveolar dry keep plays an important role, and with anti-microbial infection defensive role. Many diseases are associated with pulmonary surfactant, such as neonatal respiratory distress syndrome, adult respiratory distress syndrome, shock, pulmonary edema, acidosis and pulmonary infarction.