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神经—内分泌癌(CNE)是一种上皮细胞的恶性肿瘤,该肿瘤是由分化程度不同的神经内分泌细胞所构成。CNE是一类发展缓慢的各类肿瘤(如类癌、小细胞癌),其恶性度高,侵袭力强。小细胞CNE常发生在支气管内,罕见于消化器官。曾有人在食道、胃、胰腺、小肠和直肠内发现过该类肿瘤。 本文报道的患者为女性,51岁。既往无异常发现。因持续性咽下困难3个月于1988年5月入院。纤维镜检查显示,距齿弓24cm食道处有一高2cm溃疡性肉芽样肿物。活检为未分化癌。常规生物学检查、胸片和支气管纤维镜均未见异常。行全食管切
Neuro-endocrine carcinoma (CNE) is a malignant tumor of epithelial cells that consists of neuroendocrine cells with different degrees of differentiation. CNE is a type of tumor that develops slowly (such as carcinoid, small cell carcinoma), and it has a high degree of malignancy and strong invasiveness. Small cell CNE often occurs in the bronchus and is rare in the digestive organs. It has been found in the esophagus, stomach, pancreas, small intestine and rectum. The patient reported in this article is female and is 51 years old. No abnormalities were found in the past. Sustained dysphagia was admitted to hospital in May 1988 for 3 months. Fiberoptic examination revealed that there was a 2 cm high ulcer-like granulation mass at the esophagus 24 cm from the dental arch. The biopsy is undifferentiated cancer. No abnormalities were found in routine biological examinations, chest radiographs, and bronchial fiberscopes. Full esophageal incision