肾上腺脑白质营养不良(Adrenoleukodystrophy,ALD),是一种少见的伴性隐性遗传性疾病。欧美报告发生率1/2.5万,男性多见,临床以肾上腺皮质功能不全和迅速进行性脑白质变性引起的运动障碍、记忆力减退、视力障碍为特点。国内于1987年首次报告1例,此后仅有少数病例报告,现就我院收治的3例报告如下。 Adrenoleukodystrophy (ALD), a rare complication of inherited recessive disease. Europe and the United States reported the incidence of 1/25000, more common in men, clinically adrenal insufficiency and rapid progressive white matter degeneration caused by dyskinesia, memory loss, visual impairment as the feature. 1 case was first reported in China in 1987 and only a few cases were reported thereafter. The report of 3 cases admitted to our hospital is as follows.