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目的分析张家口市2012年疑似预防接种异常反应(Adverse Event Following Immuni zation,AEFI)的发生特征,评价AEFI监测系统的运转情况。方法通过AEFI监测系统,收集2012年张家口市AEFI个案数据,采用描述性方法对AEFI监测系统运转进行评价,对AEFI病例进行流行病学分析。结果 2012年全市17个县(区)均有AEFI数据报告,48 h内报告率为100.0%,48 h内调查率为100.0%。全市AEFI监测系统共收到个案448例,其中﹤1岁占58.0%,男女性别比例为1.196∶1。报告的AEFI中国家免疫规划(NIP)疫苗占95.5%,一般反应占97.5%,预防接种异常反应占2.5%。估算全市NIP疫苗常见预防接种异常反应报告发生率为11.53/10万,全部治愈或好转。结论张家口市AEFI监测灵敏性和监测质量尚需提高,小年龄儿童及NIP疫苗的接种要重点监测。
Objective To analyze the occurrence characteristics of AEFI in Zhangjiakou in 2012 and evaluate the operation of AEFI monitoring system. Methods AEFI monitoring system was used to collect the data of AEFI cases in Zhangjiakou City in 2012. The descriptive method was used to evaluate the operation of AEFI monitoring system and the epidemiological analysis was performed on AEFI cases. Results AEFI data was reported in 17 districts (districts) in 2012, with a reported rate of 100.0% within 48 h and a 100.0% within 48 h. The city’s AEFI monitoring system received a total of 448 cases, of which <1 year accounted for 58.0%, male to female ratio was 1.196: 1. Reported AEFI national immunization program (NIP) vaccine accounted for 95.5%, the general response accounted for 97.5%, vaccination abnormal response accounted for 2.5%. Estimates of the city’s NIP vaccine common vaccination abnormal response report was 11.53 / 100,000, all cured or improved. Conclusion The sensitivity and monitoring quality of AEFI in Zhangjiakou need to be improved. The vaccination of young children and NIP vaccine should be monitored.