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血液流变学是研究血液与血管运动——流动与变形——的一个专门学科.本文着重讨论其在心脑血管疾病防治中的关键意义. 血液流变学临床应用中的基本概念是血液高粘滞综合征.它是十余年前由Dintenfass根据应用流变学于临床的经验而提出的.这一概念认为,血液中存在一系列“粘滞因素”,这些因素的升高,可导致血液的高粘滞状态,即血流缓慢或瘀滞.血液高粘滞因素包括:(1)与血浆有关的因素:例如血浆粘度;血浆内生化组分的含量与比例,如血脂水平,白蛋白与纤维蛋白原的含量与比值等.(2)与血细胞有关的因素:一般情况下红细胞影响最大,其数量与质量(聚集程度,变形能力等)
Hemorheology is a specialized discipline that studies the movement of blood and blood vessels - flow and deformation - This article focuses on the key aspects of prevention and treatment of cardiovascular and cerebrovascular diseases.The basic concept of clinical application of hemorheology is high blood Viscous syndrome, which was proposed by Dintenfass more than a decade ago based on the clinical experience of applied rheology, suggests that there is a series of “viscous factors” in the blood that can lead to The high viscosity state of the blood, that is, slow or stasis of blood flow High blood viscosity factors include: (1) plasma-related factors such as plasma viscosity and content and proportion of plasma biochemical components such as blood lipid levels, Protein and fibrinogen content and ratio, etc .. (2) and blood cells-related factors: under normal circumstances, the most affected red blood cells, the number and quality (aggregation degree, deformation capacity, etc.)