概况化学物质能引起癌症并不是新问题,Percivall Pott 于1775年最早发现扫烟囱工人患阴囊癌,他认为这和接触煤烟灰有关。1915年,日本学者用煤焦油涂抹家兔皮肤诱发皮肤癌成功。以后,通过大量职业性肿瘤流行病学调查和动物实验,特别是近年来发展的快速筛选方法,陆续发现了许多有致癌作用的化学物质。据近年文献报导,在已知的约400多万种化学物质中,作过致癌 Overview Chemicals can cause cancer is not a new problem, Percivall Pott first found in 1775 Sweep chimney workers suffering from scrotal cancer, he believes that contact with the soot. In 1915, Japanese scholar using coal tar coated rabbit skin induced skin cancer success. Later, through a large number of occupational cancer epidemiological investigations and animal experiments, especially in recent years the rapid development of screening methods, one after another found a number of carcinogenic chemicals. According to recent reports in the literature, about 4 million kinds of chemicals are known to have been carcinogenic