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回顾性分析手术、立体定向放射手术和放疗治疗脑转移瘤的疗效。1991年1月至1995年12月,59例脑转移瘤分别采用手术(10例),放射手术(19例)和放疗(30例)治疗。手术组术后全脑照射40Gy,放射手术剂量20～30Gy(平均21.1Gy),放疗组全脑照射30～40Gy,然后缩野追加10～24Gy。手术组、放射手术组、放疗组的中位生存期分别为12.5个月、11.2个月、5.6个月;一年生存率分别为60％、47.4％、20％。手术和放射手术治疗脑转移的疗效相似(P=0.25),且明显好于常规放疗(P<0.05)。
Retrospective analysis of surgical, stereotactic radiosurgery and radiotherapy for the treatment of brain metastases. From January 1991 to December 1995, 59 cases of brain metastases were treated with surgery (10 cases), radiation (19 cases) and radiotherapy (30 cases). After surgery, the whole brain was irradiated with 40 Gy, the radiation dose was 20-30 Gy (average 21.1 Gy), and the radiation group was irradiated with 30-40 Gy of whole brain, and then the contraction field was supplemented with 10-24 Gy. The median survival time was 12.5 months, 11.2 months, and 5.6 months in the surgery, radiosurgery, and radiotherapy groups; the one-year survival rates were 60%, 47.4%, and 20%, respectively. The efficacy of surgical and radiosurgical treatment of brain metastases was similar (P=0.25) and was significantly better than conventional radiotherapy (P<0.05).