目的　探讨慢性特发性血小板减少性紫癜 ( ITP)新的有效治疗方法　方法　 3例慢性 ITP患者行脾动脉灌注长春新碱 ( VCR)加脾动脉栓塞术 ,观察术后临床症状及血小板计数　结果　 3例术后临床症状消失 ,血小板计数上升 ,随诊 6～ 8个月以上仍稳定于正常水平 ,无感染发生　结论　脾动脉灌注VCR加栓塞治疗慢性 ITP疗效好 ,无明显副作用 Objective To explore a new effective treatment method for chronic idiopathic thrombocytopenic purpura (ITP). Methods 3 patients with chronic ITP were treated with splenic arterial perfusion of vincristine (VCR) and splenic artery embolization. Clinical symptoms and platelet counts were observed. 3 The clinical symptoms disappeared and the platelet counts increased after the operation. The follow-up of 6 to 8 months remained stable at normal levels. No infection was found. Conclusion VCR plus embolization in the splenic artery was effective in the treatment of chronic ITP without obvious side effects.