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本院出生活产新生儿4083例，经直接Coombs’试验（改良法）及／或抗体释放试验阳性诊断为新生儿ABO溶血病152例（占3．7％）其中脐血诊断105例，认为脐血作三项试验能早期诊断本病，当脐血胆红素≥51．3μmol．L（3mg／dL）时可作为发生高胆的预报指标。与常规治疗组比较，早期监测防治组高胆红素血症的发生率及胆红素峰值都明显降低（P＜0．01）；疗程缩短（P＞0．05）。肯定了早期监测防治对预防核黄疸的发生有确切的临床应用价值。
In our hospital, 4083 newborns with live births were diagnosed as neonatal ABO hemolytic disease by direct Coombs’ test (modified method) and / or antibody release test. 152 cases (3.7%) were diagnosed by cord blood and 105 cases were diagnosed as cord blood Cord blood for the three tests early diagnosis of the disease, when the umbilical cord serum bilirubin ≥ 51.3μmol. L (3mg / dL) can be used as an indicator of occurrence of high bile. Compared with the conventional treatment group, the incidence of hyperbilirubinemia and the peak of bilirubin in the early monitoring and control group were significantly decreased (P <0.01), and the course of treatment was shortened (P> 0.05). Affirmed the early monitoring and prevention of the occurrence of prevention of kernicterus has the exact clinical value.