Charcot—Marie—Tooth氏病(CMT)又称腓骨肌萎缩或神经性进行性肌萎缩症,因本病少见,易误诊。现结合我们收治的2例,分析如下: 例1:男,29岁,3年前无诱因出现双小腿无力,行走后易疲劳,小腿肌肉渐萎缩,1年前渐出现双足下垂,全身不定点肌肉痉挛,以腓肠肌好发。追问家族4代人,部分并进行了调查,无类似病人。查体:一般状况较好,双小腿肌萎缩明显,足尖下垂,不能背曲,马蹄足内翻,行走呈跨越步态,四肢末端呈手套、袜子型轻度感觉障碍,腹壁反射(-),双膝反射(+),双跟腱反射(-),病理反射(-)。腰穿结果正 Charcot-Marie-Tooth’s disease (CMT), also known as Charcot-Marie-Tooth muscle atrophy or neuropathic muscular atrophy, is rare and easily misdiagnosed. Now combined with our treatment of 2 cases, the analysis is as follows: Example 1: Male, 29 years old, three years ago, there is no incentive to appear weakness of the lower leg, walking fatigue, calf muscle atrophy, gradually emerged two years ago, foot biped, the whole body Fixed muscle spasms, to the gastrocnemius hair. 4 generations of family members were questioned, some were investigated and no similar patients were found. Physical examination: the general condition is good, double calf muscle atrophy, toe drooping, can not dorsiflexion, clubfoot varus, walking across the gait, extremities were gloves, socks mild sensory disturbance, abdominal reflex (-) , Knee reflex (+), double Achilles tendon reflex (-), pathological reflex (-). Waist wear results positive