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目的 观察术前新辅助化疗治疗老年ⅡB 期宫颈癌的临床效果.方法 回顾性分析80例术前应用TC (紫杉醇+卡铂)方案进行新辅助化疗的ⅡB 期宫颈癌老年患者的临床资料, 比较分析患者化疗前后肿瘤病灶大小、手术治疗情况及术后病理和预后等.结果 化疗后手术率为91. 25% (73/80), 化疗后可行根治术治疗的患者肿瘤直径与化疗前相比明显缩小, 差异有统计学意义(P <0. 05), 化疗效果与病理类型有关.结论 术前新辅助化疗治疗老年ⅡB期宫颈癌, 可以缩小肿瘤病灶, 提高手术治疗效果, 改善预后, 安全有效.“,”Objective To evaluate the therapeutic effect of neoadjuvant chemotherapy onⅡB-stage cervical cancer in ol-der patients. Methods A retrospective analysis was performed on the data collected from 80 older patients with stage ⅡB cervical cancer. The patients underwent TC chemotherapy regimen (paclitaxel+carboplatin) as the neoadjuvant chemotherapy before surgical operation. Tumor size, surgical procedure, postoperative pathological examination and prognosis were evaluated. Results After chemotherapy, the operation rate was 91. 25% (73/80). The tumor diameter was significantly smaller than before chemotherapy (P<0. 05). The effect of chemotherapy was related to the pathological type. Conclusion Preoperative neoadjuvant chemotherapy can reduce tumor size, improve effectiveness of surgical procedure and prognosis in older patients with ⅡB-stage cervical cancer.