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本文报告了自1991年以来对周宁县肾综合征出血热（HFRS）开展控制的效果研究。通过历年监测资料综合分析，证实了黑线姬鼠、褐家鼠和黄毛鼠是周宁县HFRS的主要宿主动物和传染源，疫区类型属姬鼠为主的混合型疫源地。自1991年以来每年坚持在春秋季节进行两次大规模的以灭野鼠为主，并灭家鼠的防制措施，使鼠密度、带病毒鼠指数大幅度下降，人群发病率比灭灵前18年年均下降54．16％，比灭鼠前5年下降67．37％。监测发现，随着灭鼠工作的深入开展，鼠种构成及带病毒状况发生变化，近年来野外针毛鼠、黑线姬鼠构成明显下降，带病毒率减少，黄毛鼠构成相对上升。
This article reports the effect of controlling HFRS in Zhouning County since 1991. Through the comprehensive analysis of monitoring data over the years, it was confirmed that Apodemus agrarius, Rattus norvegicus and Rattus rat were the main host animals and sources of infection of HFRS in Zhouning County. The epidemic area belonged to the mixed foci of Apodemus agrarius. Since 1991, every year in the spring and autumn insist on two large-scale off wild rats, and the control of domestic mice, the rat density, viral rat index dropped significantly, the incidence of the crowd than the extinction of 18 The average annual decline of 54.16%, 5 years before deratization decreased 67.37%. Monitoring found that with the in-depth development of anti-rodent work, the composition of mice and virus-bearing conditions have changed in recent years, the field of needle-hairy rats, Apodemus off-line composition decreased significantly with the virus rate decreased, Rattus composition relative rise.