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近年来治疗重症小儿肺炎应用小剂量肝素取得满意疗效,有助于短期内缓解临床症状,推测血小板参与了肺炎病理过程。本文检测16例肺炎患儿急性期和恢复期血浆内α颗粒膜蛋白(α-GMP-140)含量,以探讨血小板在肺炎发病机理中的作用。 对象与方法 一、对象 根据小儿支气管肺炎诊断标准,选择我院住院肺炎患儿16例,其中男9例、女7例,年龄4月～6岁。另在儿童保健门诊选择经检查为健康儿18例作对照,男10例,女8例,年龄1～7岁。 二、方法 应用北京医学科学院药理基础研究室提供的试剂盒,采用放免法检测血浆内α-GMP-
In recent years, the treatment of severe pneumonia in children with small doses of heparin achieved satisfactory results, help to alleviate clinical symptoms in the short term speculated that platelets involved in the pathological process of pneumonia. In this paper, 16 cases of children with pneumonia in acute and convalescent plasma α-granule membrane protein (α-GMP-140) content in order to explore the role of platelet in the pathogenesis of pneumonia. Subjects and methods First, the object According to the diagnosis of bronchial pneumonia in children, we selected 16 cases of hospitalized children with pneumonia, including 9 males and 7 females, aged 4 months to 6 years. Another child care clinic choose to check for healthy children 18 cases as a control, 10 males and 8 females, aged 1 to 7 years. Second, the method using the kit provided by the Beijing Medical Academy of Pharmacology, using radioimmunoassay plasma α-GMP-