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口咽部念珠菌感染是HIV感染者发生艾滋病的开始。感染率在11％～96％之间。HIV感染的早期出现口腔念珠菌病高度预示了病情的恶化。过去用生物型和血清型技术的研究认为白色念珠菌的口腔株仅限于HIV感染者。另一些用先进分子技术的研究则不支持这种观点。至今尚无HIV感染有关的白色念珠菌生物型分布特征的报告。本研究的目的在于:①鉴定从香港、澳大利亚、德国、英国的HIV感染者口腔标本中分离到的白色念珠菌的生物型。②比较不同生物型白色念珠菌的地理分布特点。
Candida oropharyngeal infection is the start of AIDS in HIV-infected people. The infection rate is between 11% and 96%. Early onset of HIV infection Oral candidiasis is highly predictive of exacerbations. In the past, studies on biotype and serotype technology suggested that C. albicans oral strains were restricted to HIV-infected individuals. Other studies using advanced molecular techniques do not support this view. To date, there is no report on the biotype distribution of Candida albicans related to HIV infection. The purpose of this study was to: (1) identify the Candida albicans biotypes isolated from oral specimens of HIV-infected persons in Hong Kong, Australia, Germany and the United Kingdom. ② different types of biological Candida albicans geographical distribution characteristics.