论文部分内容阅读
侵袭性纤维瘤病(aggressive fibromatosis,AF)是介于良恶性之间的交界性肿瘤,以局部浸润和高复发率为特点.AF的治疗既往以手术切除为主,但单纯手术复发率较高,盲目的手术往往造成患者机能或外形的损伤.近年来,包括内分泌治疗、手术、放疗、化疗、非甾体抗炎药物治疗、靶向药物、干扰素等多种治疗手段得到尝试,并取得一定疗效.此外,鉴于AF的惰性特征,观察等待也是多个行业指南推荐的一线方案.在AF的治疗决策上,必须综合考虑患者需求,注重机体功能和外形的保全,将非手术手段放到与手术同等地位加以考虑.“,”Multiple modalities including endocrine therapy,surgery combined with radiotherapy,chemotherapy,non-steroidal anti-inflammatory drug treatment,targeted drugs,and interferon treatment have been tried and achieved comparable success in AF treatment.In addition,based on the indolent nature of AF,follow-up observation is also recommended as first-line treatment by several guidelines.For the treatment decision of AF,the patientsexpectation must be considered.Function preservation and cosmetic requirement need to be emphasized,and non-surgical treatment should be considered as important as surgery.