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内皮细胞抑制素是一种新发现的特异的血管内皮细胞增殖抑制剂 ,它可以有效地抑制内皮细胞生长 ,对肿瘤血管形成具有强烈的抑制作用 ,在抗实体瘤方面有显著的效果 ,本文就它的发现、结构、生物学活性、作用机理及研究进展进行综述
Endostatin is a newly discovered inhibitor of vascular endothelial cell proliferation, which can effectively inhibit the growth of endothelial cells, has a strong inhibitory effect on tumor angiogenesis and has significant effects on solid tumors Its discovery, structure, biological activity, mechanism of action and research progress are reviewed