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停用三环抗抑郁药后产生撤药症状已屡见报告。撤药症状常发生在停药后25～48小时内。常出现全身不适(肌痛、鼻塞、大汗)、胃肠道(恶心、呕吐、腹泻和腹痛)和神经精神(嗜睡、淡漠、易激惹、激越、抑郁复发)等症状。有研究报导,21～55%的成年患者停用丙咪嗪后可出现某些撤药症状。为了进一步研究三环抗抑郁药的撤药反应,本文
The withdrawal of tricyclic antidepressants withdrawal symptoms have been frequently reported. Withdrawal symptoms often occur within 25 to 48 hours after withdrawal. Common symptoms such as generalized malaise (myalgia, stuffy nose, sweating), gastrointestinal tract (nausea, vomiting, diarrhea and abdominal pain) and neuropsychiatric disorders (lethargy, indifference, irritability, agitation and depression) Some studies have reported that 21 to 55% of adult patients discontinued after imipramine certain withdrawal symptoms may occur. In order to further study the withdrawal response tricyclic antidepressants, this article