由于钩端螺旋体病起病急骤,临床表现常复杂多样而严重,在发病3天内,血清内抗体量很少,病原体直接镜检一般阳性率较低,故早期漏诊、误诊机会较多。我院所收治87例中,早期误诊或漏诊者有33例,误诊率为37.93%,周庆均等报告573例,误诊率为25.3%。近三年来对本病警惕性及诊断知识虽均有所提高,惟早期诊断国内报告误诊率仍达21.7～22.6%。本病能否得到早期诊断、 Due to the rapid onset of leptospirosis, clinical manifestations often complex and diverse and serious, within 3 days of onset, the amount of serum antibody is very small, the direct positive rate of pathogens direct microscopy is low, so early missed diagnosis, misdiagnosis more. 87 cases admitted to our hospital, early misdiagnosis or missed diagnosis of 33 cases, the misdiagnosis rate was 37.93%, 573 cases were equally reported by Zhou Qing, the misdiagnosis rate was 25.3%. In the recent three years, the vigilance and diagnosis knowledge of this disease have all been improved, but the misdiagnosis rate of early diagnosis of domestic reports still reaches 21.7 ~ 22.6%. The disease can get early diagnosis,