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作者研究了11例伴有11q 易位的急性白血病(AL)的临床、形态和免疫学特征。病例均系1982年3月至1985年5月间住院的日本人.染色体标本取自化疗前的骨髓.外周血或淋巴结。采用 Q 或 G 显带进行分析,结果3例为 t(9;11)(p22;q23),1例为变异型 t(9;11)(指11号与伴有臂间倒位的9号之间的易位),3例为 t(11;19)(q23;p13),2例为t(1;11)(p32;q23),1例为 t(10;11)(p15;q22或23),1例为 t(11;17)(q23;q25)。11号染色体上的断裂点集中在 q23带上。患者年龄4天—52岁,其中不满1岁者5例,
The authors studied the clinical, morphological, and immunological characteristics of 11 patients with 11q translocations of acute leukemia (AL). All patients were Japanese hospitalized between March 1982 and May 1985. Chromosome samples were obtained from the bone marrow before chemotherapy, peripheral blood or lymph nodes. Using Q or G banding analysis, the results of 3 cases of t (9; 11) (p22; q23), 1 case of variant t (9; 11) ), T (11; 19) (q23; p13) in 3 patients and t (1; 11) (p32; q23) in 2 patients and t Or 23) and 1 case was t (11; 17) (q23; q25). The breakpoint on chromosome 11 is focused on the q23 band. Patients aged 4 days -52 years, of whom less than 1 year in 5 cases,