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目的:探讨补肺活血汤联合噻托溴铵治疗慢性阻塞性肺疾病的疗效.方法:选取慢性阻塞性肺疾病患者68例,按入院先后分为两组,每组34例,治疗组予补肺活血汤联合噻托溴铵治疗,对照组予噻托溴铵治疗,比较两组治疗后SGRQ(圣乔治呼吸)问卷评分、证候积分、肺功能以及外周血T淋巴细胞亚群水平.结果:治疗组治疗后SGRQ问卷中症状、活动能力、对日常生活影响和总分4项评分均低于对照组(P＜0.05);治疗组治疗后证候积分低于对照组,差异有统计学意义(P＜0.05);治疗组治疗后外周血中CD4+T淋巴细胞和CD4+/CD8+水平高于对照组,CD8+水平低于对照组,差异均有统计学意义(P＜0.05);治疗组治疗后肺功能中FVC、FEV1、FEV1/FVC和FEV1预计值均高于对照组,差异均有统计学意义(P＜0.05).结论:补肺活血汤联合噻托溴铵治疗慢性阻塞性肺疾病临床预后较好,恢复快,病情控制更稳定,肺功能改善明显.“,”Objective:To explore the clinical effect of Bufei Huoxue Decoction (补肺活血汤,BFHXD)combined with tiotropium bromide on patients with chronic obstructive pulmonary disease.Methods:68 patients with chronic obstructive pulmonary disease were selected,and divided into two groups,each group of 34 cases,the observation group was treated with Bufei Huoxue Decoction combined with tiotropium,the control group was treated with tiotropium bromide,and the scores of SGRQ (St.George's breath) questionnaire,syndrome score,lung function,and peripheral blood T lymphocyte subsets were compared.Results:The scores of the symptoms,activity,the impact on the daily life and the total score of the SGRQ questionnaire in the observation group were lower than those in the control group,the difference was statistically significant (P＜0.05);The syndrome score in the observation group after treatment was lower than that of the control group,the difference was statistically significant (P＜0.05);The level of CD4+ T lymphocytes and CD4+/CD8+ in the peripheral blood of the observation group was higher than that of the control group,the level of CD8+ was lower than that of the control group,the difference was statistically significant (P＜0.05);The levels of FVC,FEV1,FEV1/FVC and FEV1 in the lung function of the observation group were higher than those in the control group,the difference was statistically significant (P＜0.05).Conclusion:Bufei Huoxue Decoction combined with tiotropium in the treatment of chronic obstructive pulmonary disease in patients has good clinical prognosis,faster recovery,more stable disease control,and improved lung function significantly.