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60年代以来,在天津(T)-上海(S)-遵义(Z)等地相继建立了T638、L6565、L615、L795、L783小鼠白血病和SRS淋巴瘤瘤株,形成一个具有我国特点的实验性白血病系统,它们有共同的起源,在脾脏、胸腺和淋巴结的超薄切片中都可观察到A型和C型病毒颗粒,并证明病毒具有致白血病活性。作者对这些白血病株和淋巴瘤的生物学、病理学、免疫学、超微结构和病毒的分离提纯、逆转录酶活性以及前病毒DNA等方面等进行了系统的研究,结果表明T-S-Z白血病系统是研究白血病的病因-发病学和实验性治疗的良好模型。《实验性T-S-Z白血病系统的研究(1980～1986)》概述作者的此项研究成果,值得一读。
Since the 1960s, T638, L6565, L615, L795, and L783 mouse leukemia and SRS lymphoma strains have been established in Tianjin (T)-Shanghai (S)-Zunyi (Z) and other regions, forming an experiment with Chinese characteristics. In the leukemia system, they have a common origin. Type A and type C virus particles can be observed in ultrathin sections of the spleen, thymus, and lymph nodes, and the virus is shown to have leukemia-inducing activity. The authors systematically studied the biology, pathology, immunology, ultrastructure and virus purification, reverse transcriptase activity, and proviral DNA of these leukemia strains and lymphomas. The results indicate that the TSZ leukemia system is To study the etiology of leukemia - a good model of pathology and experimental treatment. The “Study of experimental T-S-Z leukemia system (1980-1986)” outlines the author’s findings and is worth reading.