Objective:To explore the efficacy of interventional therapy for chronic atherosclerotic occlusive disease of the lower extremity.Methods:Fifty-six cases of simple atherosclerotic occlusive disease of lower extremity were divided into 3 types according to the location of occlusion,including 17 cases of abdominal aorta-iliac artery,18 cases of iliac-femoral artery,and 21 cases of inferior popliteal artery.Catheter and guide wire combined with blunt dissection and subtle banding were used to dredge the occluded vessels,and stents were implanted when interlayer appeared.Results:After the treatment,46 cases of occlusion were dredged(82.1%),6 cases remained occluded with the same symptoms(10.7%),and 4 cases had severer symptoms(7.1%).Among the 46 successful cases,there were 16 cases of abdominal aorta-iliac artery(94.1%),16 cases of iliac-femoral artery(88.9%) and 14 cases of inferior popliteal artery.artery(66.6%).There was no statistical difference between the abdominal aorta-iliac artery cases and iliac-femoral artery cases(P>0.05),but there was statistical difference between these two types and the inferior popliteal artery cases(P<0.05).In the successful cases,9 cases of abdominal aorta-iliac artery(52.9%),10 cases of iliac-femoral artery(55.5%) and 10 cases of inferior popliteal artery(33.3%) had 5-10 cm of occlusion,with no statistical difference between the first two types(P>0.05),but with statistical difference between the first two types and the third type(P<0.05).Compared with the 14 dredged cases(71.4%),the 7 cases(33.3%) of inferior popliteal artery cases had richer compensatory circulation(P<0.05).Conclusion:It’s safe and effective to treat simple atherosclerotic occlusive disease of the lower extremity with interventional therapy.The location and length of occlusion and the abundance of compensatory circulation had effect on the therapy. Objective: To explore the efficacy of interventional therapy for chronic atherosclerotic occlusive disease of the lower extremity. Methods: Fifty-six cases of simple atherosclerotic occlusive disease of lower extremity were divided into 3 types according to the location of occlusion, including 17 cases of abdominal aorta-iliac artery, 18 cases of iliac-femoral artery, and 21 cases of inferior popliteal artery. Catheter and guide wire combined with blunt dissection and subtle banding were used to dredge the occluded vessels, and stents were implanted when there was .Results: After the treatment, 46 cases of occlusion were dredged (82.1%), 6 cases were occluded with the same symptoms (10.7%), and 4 cases had severer symptoms (7.1%). Among the 46 successful cases, there were 16 cases of There was no statistical difference between the abdominal aorta-iliac artery (94.1%), 16 cases of iliac-femoral artery (88.9%) and 14 cases of inferior popliteal artery .artery (66.6%). There were statistically difference between these two types and the inferior popliteal artery cases (P <0.05) .In the successful cases, 9 cases of abdominal aorta-iliac artery (52.9% ), 10 cases of iliac-femoral artery (55.5%) and 10 cases of inferior popliteal artery (33.3%) had 5-10 cm of occlusion, with no statistical difference between the first two types (P> 0.05), but with statistical difference between the first two types and the third type (P <0.05) .Compared with the 14 dredged cases (71.4%), the 7 cases (33.3%) of the inferior popliteal artery cases had richer compensatory circulation : It’s safe and effective to treat simple atherosclerotic occlusive disease of the lower extremity with interventional therapy. The location and length of occlusion and the abundance of compensatory circulation had effect on the therapy.