二甲基亚砜(DMSO)在有机合成中已有广泛的应用。迄今为止,有关以DMSO氧化醇的工作,绝大部分都是在加入活化剂(SOCl_2、(COCl)_2、SO_2Cl_2、Py·SO_2、COCl_2……)的情况下进行的。在空气中,单独使用DMSO的报导很少(只限于芳香醇)。初步结果表明,DMSO在空气中,适当的温度下,能将脂肪醇氧化成相应的醛或酮,结果良好(见下表)。 Dimethyl sulfoxide (DMSO) has been widely used in organic synthesis. So far, most of the work on the alcohol oxidation with DMSO has been carried out with the addition of activators (SOCl_2, (COCl) _2, SO_2Cl_2, Py · SO_2, COCl_2 ...). In air, there is very little reported use of DMSO alone (aromatic alcohols only). The preliminary results show that DMSO can oxidize fatty alcohols to the corresponding aldehydes or ketones in air at appropriate temperatures with good results (see table below).