erbA 基因编码富含半胱氨酸区,此区与类固醇激素受体 DNA 结合区高度同源,其氨基酸顺序与小鼠,大鼠及人的糖皮质激素受体和鸡与人雌激素受体几乎完全相同。鸡和人 erbA 蛋白质在此区仅有90%的同源性,可能为不同基因编码功能相似而又不完全相同的蛋白质。为分离更多的 erbA 基因家族 The erbA gene encodes a cysteine-rich region that is highly homologous to the binding domain of the steroid hormone receptor DNA, the amino acid sequence of which is closely related to the glucocorticoid receptor of mice, rats and humans, and the human androgen receptor of chicken and human Almost exactly the same. The chicken and human erbA proteins share only 90% homology in this region, probably because different genes encode proteins with similar but not identical functions. To isolate more of the erbA gene family