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目的 :探讨血清可溶性转铁蛋白受体在缺铁性贫血治疗后的变化及意义。方法 :对 2 2例缺铁性贫血的小儿进行 6周补铁治疗 ,分别于治疗前 ,治疗 2周、4周及 6周后 EL ISA法测定 s- Tf R,同时检测 Hb、SF。结果 :治疗 2周后 s- Tf R降低、Hb升高 ,均较治疗前明显变化 ;SF4周后方有上升 ,与治疗前比 ,差异显著 ;6周后各指标均至正常范围。结论 :s- Tf R在缺铁性贫血补铁治疗后迅速降低 ,可作为评价缺铁性贫血治疗效果的指标。
Objective: To investigate the changes and significance of serum soluble transferrin receptor in the treatment of iron deficiency anemia. Methods: Twenty-two infants with iron-deficiency anemia were treated with iron supplementation for 6 weeks. The levels of s-Tf R, EL and Hb were measured before treatment, 2 weeks, 4 weeks and 6 weeks after treatment. Results: After 2 weeks of treatment, the s-Tf R decreased and Hb increased, all of which were significantly changed compared with those before treatment. After 4 weeks, the levels of sTf increased and were significantly different from those before treatment. After 6 weeks, all indexes were within the normal range. CONCLUSIONS: s-Tf R is rapidly reduced after iron-deficiency anemia treatment, which can be used as an index to evaluate the therapeutic effect of iron-deficiency anemia.