尼扎替丁(Nizatidine,N)是新的强效H_2受体拮抗剂,作者报道N与雷尼替丁(R)两药300mg夜间1次服用在短程治疗十二指肠溃疡(DU)时效果和安全性的双盲研究结果。 138例溃疡直径至少5mm的活动性DU患者,双盲平均分成R组和N组。观察溃疡愈合及止痛效果。治疗4周时行内镜检查,如溃疡未痊愈再治疗4周后复查,每2周记录1次临床情况。治疗4周后,N组有58例(84.1％),R Nizatidine (N) is a potent and potent H 2 receptor antagonist. The authors report that 300 mg of both N and ranitidine (R) are taken once daily during the short-range treatment of duodenal ulcers (DU) Results and double-blind study of safety. 138 patients with active DU with at least 5mm ulcer diameter were equally divided into R and N groups. Observation of ulcer healing and analgesic effect. Endoscopic treatment of 4 weeks endoscopy, such as ulcer healing after 4 weeks of review, recorded once every 2 weeks clinical situation. After 4 weeks of treatment, 58 patients (84.1%) in group N,