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糖尿病酮症酸中毒(DKA)的死亡率在较大医疗中心为5～10%,非专科医疗中心为20～30%,在老年人可高达50%。其治疗目标主要是恢复其代谢紊乱(尤其是糖和脂肪代谢紊乱),矫正水、电解质,酸硷平衡,控制感染等并发症。其中短效胰岛素治疗占重要地位,但其剂量和方法上尚无合理的统一意见。过去一直沿用大剂量胰岛素间歇疗法,虽取得了肯定的疗效,但是否必须用如此大的剂量(首剂胰岛素多超过40单位,6～24小时内总量可达300～500单位),
Mortality rates for diabetic ketoacidosis (DKA) range from 5 to 10% in larger centers, 20 to 30% in non-specialist centers and up to 50% in the elderly. The treatment goal is to restore its metabolic disorders (especially sugar and fat metabolism disorders), correct water, electrolyte, pH balance, infection control and other complications. Among them, short-acting insulin treatment plays an important role, but there is no reasonable consensus on the dosage and method. In the past, high-dose insulin intermittent therapy has been used, although the positive effect has been obtained, but it is necessary to use such a large dose (the first dose of insulin more than 40 units, the total amount of 300 to 500 units within 6 to 24 hours)