目的　分析探索结肠癌近年来发病的新特点及临床意义。方法　回顾我院 8年结肠镜检查出的2 6 1例结肠癌资料年 (年龄 19～ 86岁 ) ,前后 4年的病例进行比较分析。结果　发病率上升迅速 ,前 4年占2 8 7%、后 4年占 71 3% ,中位年龄前 4年 5 4岁、后 4年 6 3岁 ,组织分型及临床表现也有不同。结论　结肠镜检查有助于早期结肠癌炎性肠病的鉴别诊断。 Objective To analyze and explore the new features and clinical significance of colon cancer in recent years. Methods A retrospective review was conducted on the data of 261 cases of colon cancer (aged 19-86 years) collected in our hospital during 8 years of colonoscopy. The cases were analyzed before and after 4 years. Results The incidence rate rose rapidly, accounting for 28.7% in the first 4 years, 71.3% in the latter 4 years, 54 years before the median age and 63 years after the 4 years. There was also a difference in the type and clinical manifestations of the disease. Conclusion Colonoscopy is helpful for the differential diagnosis of early colon cancer with inflammatory bowel disease.