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气管内给氧(Transtracheal oxygen,TTO_2)可以改善慢性低氧血症患者的氧合作用,减轻呼吸困难和提高运动耐受性,对后者的机理尚不清楚。7例慢性低氧血症患者,男1例,女6例,平均年龄61±7.4岁,2例患COPD,5例患严重限制性肺疾病。当患者(经气管或经口腔)接受不同量的氧而达到相同程度的氧合作用时,测定吸气分钟通气量(V_(?))、呼气分钟通气量(V_E)、呼吸频率(RR),潮气量(V_T)、耳垂血氧饱和度(O_2 Sat)及动脉血气分析等参数。结果表明在相似的PaO_2条件下,用TTO_2患者的V_(?)较经口给氧者下降,降低程度取决于气管内
Transtracheal oxygen (TTO_2) can improve oxygenation, alleviate dyspnea and improve exercise tolerance in patients with chronic hypoxemia, and the mechanism of the latter is unclear. Seven patients with chronic hypoxemia, 1 males and 6 females, mean age 61 ± 7.4 years, 2 patients with COPD, 5 patients with severe restrictive lung disease. Ventilatory minute ventilation (V_ (?)), Expiratory minute ventilation (V_E) and respiratory rate (RR) were measured when patients received different amounts of oxygen through the trachea or the oral cavity to achieve the same degree of oxygenation , Tidal volume (V_T), blood oxygen saturation (O_2 Sat) and arterial blood gas analysis parameters. The results showed that in similar conditions of PaO_2, patients with TTO_2 V_ (?) Decreased compared with oral oxygen supply, the degree of reduction depends on the endotracheal