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无精子症和严重的少弱畸精子症占男性不育的40%~50%[1]。Y染色体长臂无精子因子(azoospermia fac-tor,AZF)区域的DAZ(deleted in azoospermia,DAZ)基因的缺失是男性精子生成障碍的重要原因。10%~15%无精子者和5%~10%严重少精子者存在Y染色体DAZ基因的缺失[2]。本文就DAZ基因的?
Azoospermia and severe oligozoospermia accounted for 40% to 50% of male infertility [1]. Deletion of the DAZ (deleted in azoospermia) gene in the azoospermia fac-tor (AZF) region of the Y chromosome is an important cause of male spermatogenesis. 10% to 15% of azoospermic and 5% to 10% of severe oligospermia exist Y chromosome DAZ gene deletion [2]. This article on the DAZ gene?