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目的观察奥美拉唑与西沙必利联合用药对于功能性消化不良患者生活质量的影响。方法 120例功能性消化不良患者,随机将患者分为联合用药组、对照组1和对照组2,各40例。联合用药组使用奥美拉唑和西沙必利联合治疗,对照组1单独使用奥美拉唑进行治疗,对照组2单独使用西沙必利进行治疗。比较三组患者的治疗效果。结果联合用药组患者治疗有效率为87.5%,均高于对照组1的65.0%、对照组2的57.5%,差异具有统计学意义(P<0.05)。结论功能性消化不良的不良症状严重影响患者的生活质量,联合使用奥美拉唑和西沙必利可以有效缓解病情,在一定程度上改善了患者的生活质量,效果显著。
Objective To observe the effect of combination of omeprazole and cisapride on quality of life in patients with functional dyspepsia. Methods A total of 120 patients with functional dyspepsia were randomly divided into two groups: control group (1) and control group (40). The combination group was treated with combination of omeprazole and cisapride, while the control group 1 was treated with omeprazole alone. The control group 2 was treated with cisapride alone. Compare the treatment effect of three groups of patients. Results The effective rate of treatment in combination group was 87.5%, which was higher than 65.0% in control group 1 and 57.5% in control group 2, the difference was statistically significant (P <0.05). Conclusions The adverse symptoms of functional dyspepsia seriously affect the quality of life of patients. Combined use of omeprazole and cisapride can effectively alleviate the condition, and improve the quality of life of patients to a certain extent, with a significant effect.