宫颈癌放疗后致放射性膀胱炎与膀胱癌(附7例报告)

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目的:减少宫颈癌放疗后放射性膀胱炎及膀胱癌的发生。方法:结合文献分析1975~1997年收治的宫颈癌放疗后引起的放射性膀胱炎7例,其中并发膀胱癌5例。并就其临床表现特点及诊断与治疗应注意的问题进行讨论。结果:7例宫颈癌放疗后发生急性放射性膀胱1例,停止放疗后经对症处理痊愈;发生慢性放射性膀胱炎6例,分别经对症处理、膀胱镜下冲洗清除血块、电灼止血痊愈。并发膀胱癌5例,死亡2例,行经尿道膀胱肿瘤切除术3例。结论:放疗对膀胱有损伤及致癌作用,可引起放射性膀胱炎及膀胱瘤。行宫颈癌放疗时应注意保护膀胱,以减少放射性膀胱炎及膀胱癌的发生。 Objective: To reduce the incidence of radiation cystitis and bladder cancer after radiotherapy of cervical cancer. Methods: Combined with the literature analysis of 7 cases of radiation cystitis caused by radiotherapy of cervical cancer admitted from 1975 to 1997, including 5 cases of bladder cancer. And to discuss its clinical features and diagnosis and treatment should pay attention to the issues discussed. Results: In 7 cases of cervical cancer, 1 case of acute radioactive bladder occurred after radiotherapy and was cured by symptomatic treatment after stopping radiotherapy. 6 cases of chronic radiation cystitis occurred. After symptomatic treatment and cystoscopic flushing, blood clots were removed and electrocautery hemostasis was cured. 5 cases of bladder cancer, 2 died, 3 cases of transurethral resection of the bladder tumor. Conclusion: Radiation on bladder injury and carcinogenesis, can cause radiation cystitis and bladder tumor. Cervical cancer radiotherapy should pay attention to the protection of the bladder to reduce the incidence of radiation cystitis and bladder cancer.
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