论文部分内容阅读
目的 :了解原发性肾病综合征 (PNS)患儿的血脂及载脂蛋白的变化。方法 :测定 2 0例原发性肾病综合征 (PNS)患儿血脂及载脂蛋白 ,并与对照组比较。结果 :PNS患儿组的血清总胆固醇 (TCH) ,游离胆固醇 (F- ch) ,胆固醇酯 (Che) ,甘油三酯 (TG) ,磷酯 (PL ) ,及载脂蛋白 B均较对照组显著升高 (P <0 .0 1) ,而 Apo A1差异不大 (P >0 .0 5 )。PNS组治疗前后血脂及载脂蛋白对比也有统计学差异。结论 :血脂变化可作疗效判断指标之一。
Objective: To understand the changes of blood lipids and apolipoproteins in children with primary nephrotic syndrome (PNS). Methods: Serum lipids and apolipoproteins in 20 children with primary nephrotic syndrome (PNS) were measured and compared with the control group. Results: The levels of serum total cholesterol (TCH), free cholesterol (F-ch), cholesteryl ester (Che), triglyceride (TG), phospholipid (PL) and apolipoprotein B in children with PNS were significantly higher than those in control group (P <0.01), while Apo A1 was not significantly different (P> 0.05). PNS group before and after treatment of blood lipids and apolipoprotein were also statistically significant differences. Conclusion: The change of blood lipid can be used as one of the indicators of curative effect.