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为了考察配伍用药的合理性、减少用药次数,研究了磷酸克林霉素(C)在各种贮存条件下与三种氨基糖甙类:硫酸阿米卡星(A)、硫酸庆大霉素(G)和硫酸妥布霉素(T)在玻璃瓶或塑料袋中混合后的稳定性和可配伍性。并在同一溶液和相同贮存条件下检测各个抗生素的稳定性。将C 与A 于玻璃瓶装100 ml 0.5%的葡萄糖(D5W)及0.9%氯化钠(NaCl)水溶液中混和。目测澄明度和测定自混合时起至48h 内的pH 值和抗生素浓度。观察期间应在自然光照下室温贮存。另分别将C 与
In order to investigate the rationality of drug compatibility and to reduce the number of drugs used, the effect of clindamycin phosphate (C) with three aminoglycosides under the various storage conditions: amikacin sulfate (A), gentamicin sulfate (G) and tobramycin sulfate (T) in glass bottles or plastic bags after mixing the stability and compatibility. The antibiotics were tested for stability in the same solution and under the same storage conditions. C and A were mixed in a glass bottle with 100 ml of 0.5% dextrose (D5W) and 0.9% sodium chloride (NaCl) in water. Visual clarity and determination of pH value and antibiotic concentration from 48 hours after mixing. During observation should be stored under natural light at room temperature. The other will be C and