脊柱是恶性肿瘤常见侵犯部位,根据不同文献报道,脊柱转移瘤发生率为10%~15%,10%~20%的脊柱转移瘤患者会发展成脊柱转移瘤脊髓压迫症~([1-3])。脊柱转移瘤细胞产生的细胞因子打破溶骨与成骨平衡并促进肿瘤生长,形成骨质破坏恶性循环~([4-6])。背部疼痛和神经功能障碍是脊柱转移瘤的主要临床表现。脊柱转移瘤是恶性肿瘤晚期,治疗以患者生活质量为中心,提倡多学科联合合作,主要包括外科开放性手术~([7-9]),微创成形术,放化疗 Spine is a common malignant tumor, according to different reports, the incidence of spinal metastases is 10% to 15%, 10% to 20% of patients with spinal metastases will develop spinal metastatic spinal cord compression ~ ([1-3 ]). Cytokines produced by spinal metastatic cells break the balance between osteolysis and osteogenesis and promote tumor growth, forming a vicious cycle of bone destruction (4-6). Back pain and neurological dysfunction are the main clinical manifestations of spinal metastases. Spinal metastases are advanced malignant tumors, the quality of life of patients as the center of treatment, advocate multidisciplinary joint cooperation, including surgical open surgery ~ ([7-9]), minimally invasive surgery, radiotherapy and chemotherapy