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对１４２例癫痫病人进行间歇期ＳＰＥＣＴ局部脑血流显像，并与脑ＣＴ、ＭＲＩ、ＥＥＧ、皮质脑电图（ＥＣｏＧ）及手术病理结果进行比较。结果表明，ＳＰＥＣＴ阳性率最高（７５．４％），ＣＴ和ＭＲＩ分别为５２．０％和５６．７％．ＳＰＥＣＴ能准确定位癫痫灶，与埋藏式ＥＣｏＧ或术中ＥＣｏＧ标测结果（ｎ＝５１）的符合率达９２．０％。致痫灶的病理改变多为隐匿性脑血管畸形、胶质增生、局灶性神经元固缩、变性及排列紊乱等。研究表明ＳＰＥＣＴ局部脑血流显像是诊断癫痫病灶的有效方法，灵敏度优于ＣＴ和ＭＲＩ，定位价值优于ＥＥＧ，对于制订癫痫的手术治疗方案有一定帮助。
Intermittent SPECT regional cerebral blood flow imaging was performed in 142 patients with epilepsy and compared with brain CT, MRI, EEG, ECoG and surgical pathology. The results showed that the highest positive rate of SPECT (75.4%), CT and MRI were 52.0% and 56.7%. SPECT can accurately locate epileptic foci, and the coincidence rate with buried ECoG or intraoperative ECoG mapping (n = 51) is 92.0%. Most of the pathological changes of epileptogenic lesions occult cerebrovascular malformations, glial hyperplasia, focal neuronal pyknosis, degeneration and arrangement disorders. Studies have shown that SPECT is an effective method for the diagnosis of epilepsy lesions. The sensitivity is better than that of CT and MRI, and the value of localization is better than that of EEG. It is helpful for the surgical treatment of epilepsy.