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在Ｌａｎｇｅｄｏｒｆｆ离体大鼠心脏模型上比较了去冠脉内皮（实验组）和保留冠脉内皮（对照组）的心肌再灌注损伤。结果：实验组的左室峰值和最大升降速度、心肌超氧化物歧化酶及ＡＴＰａｓｅ活性明显高于对照组（Ｐ＜０．０５），而冠脉灌注压和冠脉流出液中乳酸脱氢酶及磷酸肌酸激酶、心肌过氧化产物丙二醛则明显低于对照组（Ｐ＜０．０５）。表明：去冠脉内皮可减轻心肌再灌注损伤。提示：冠脉内皮细胞在心肌再灌注损伤中起重要作用。
Myocardial reperfusion injury to coronary artery endothelium (experimental group) and preserved coronary artery endothelium (control group) were compared in a Langedorff isolated rat heart model. Results: The left ventricular peak and maximum velocity, myocardial superoxide dismutase and ATPase activity in the experimental group were significantly higher than those in the control group (P <0.05), but coronary perfusion pressure and coronary effluent lactate dehydrogenase And phosphocreatine kinase, myocardial malondialdehyde peroxide product was significantly lower than the control group (P <0.05). Decreased myocardial reperfusion injury: Tip: Coronary endothelial cells play an important role in myocardial reperfusion injury.