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本文对呼吸道合胞病毒（RSV）重症毛细支气管炎（毛支）患儿70例及38例正常儿应用单克隆抗体进行外周血T淋巴细胞亚群检测，显示了急性期CD_3，CD_4、CD_8细胞均明显低于正常儿，CD_4/CD_8比值增高，恢复期CD_4细胞明显增多，CD_3、CD_8细胞呈升高趋势，推测RSV感染有细胞免疫受损，T细胞免疫功能低下和CD_8细胞缺陷是发生喘鸣的机制。本文还探讨了年龄、喘憋程度和临床特点，为被动免疫疗法提供了依据。
In this paper, peripheral blood T lymphocyte subsets were detected by monoclonal antibody in 70 children with severe bronchiolitis (bronchiolitis) and 38 normal children with respiratory syncytial virus (RSV). The results showed that acute phase CD_3, CD_4 and CD_8 cells CD_4 / CD_8 ratio was significantly higher than that in normal children, CD_4 and CD_8 cells were significantly increased in convalescent stage, while CD_3 and CD_8 cells showed an increasing trend. It was speculated that RSV infection had cellular immunity damage, T cell immunodeficiency and CD_8 deficiency Ming mechanism. This article also discusses the age, wheezing and clinical features, providing a basis for passive immunotherapy.