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目的提高临床医生对甲状腺功能减退症(甲减)并发急性呼吸衰竭的认识,减少误诊,提高救治率。方法对2002年11月-2011年6月收治的6例甲减并发急性呼吸衰竭患者予以有创机械通气及早期使用左旋甲状腺素治疗,使病症得以控制和治愈。结果患者使用有创机械通气治疗平均7 d,住院治疗14～43 d,平均(28.6±14.4)d,5例治愈,1例死亡。结论甲减并发呼吸衰竭早期使用机械通气及甲状腺激素替代治疗可提高抢救成功率。
Objective To improve clinicians’ understanding of hypothyroidism (Hypothyroidism) complicated with acute respiratory failure, reduce misdiagnosis and improve the treatment rate. Methods Six cases of hypothyroidism with acute respiratory failure admitted from November 2002 to June 2011 were treated with invasive mechanical ventilation and early use of L-thyroxine to control and cure the disease. Results The patients were treated with invasive mechanical ventilation for an average of 7 days and hospitalized for 14 to 43 days (mean, 28.6 ± 14.4 days). Five patients were cured and one died. Conclusion hypothyroidism with respiratory failure early use of mechanical ventilation and thyroid hormone replacement therapy can improve the success rate of rescue.