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目的探究局部晚期乳腺癌新辅助化疗的疗效。方法采取TAC或者AC→P方案对II~ⅢC期乳腺癌进行治疗,在术前进行4~8周期的化疗,观察治疗效果。结果超声结果显示,在4个周期化疗之后,TAC方案与AC→P方案疗效差异均有统计学意义(P<0.05),治疗总有效率为77.08%,病情总控制率达到93.75%,保乳率为18.75%。结论新辅助化疗在局部晚期乳腺癌临床治疗中,能够有效缩小肿瘤体积,达到临床降期的目的 ,术前对浸润性乳腺癌进行新辅助化疗能够提高对肿瘤的控制效果,提升保乳率。
Objective To investigate the effect of neoadjuvant chemotherapy in locally advanced breast cancer. Methods TAC or AC → P program for stage II ~ Ⅲ C breast cancer treatment, preoperative 4 to 8 cycles of chemotherapy to observe the therapeutic effect. Results The results of ultrasound showed that after 4 cycles of chemotherapy, the difference between TAC and AC → P was statistically significant (P <0.05). The total effective rate was 77.08% and the overall disease control rate was 93.75% The rate is 18.75%. Conclusion Neoadjuvant chemotherapy in locally advanced breast cancer clinical treatment, can effectively reduce the size of the tumor, to achieve the purpose of clinical drop. Preoperative neoadjuvant chemotherapy for invasive breast cancer can improve the tumor control effect and enhance the rate of breast-conserving.