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复方苯已哌啶用于治疗非感染性腹泻,婴幼儿使用不当可致中毒,重者可危及生命。我科于近10年间收治复方苯已哌啶中毒患儿31例,应用纳洛酮抢救效果显著,现将结果报告如下。1临床资料1.1病例选择所有病例选自本院急诊和住院的患儿共31例,男17例,女14例。年龄:4月-1岁11例,-2岁9例,-3岁8例,-5岁3例。1992年3月-1996年7月15例作为对照组(未用纳洛酮),其中男7例,女8例,把1996年7月-2002年11月16例作为治疗组,其中男10例,女6例。所有病例中12例为误服,19例未遵医嘱超量口服,误服最大量为20片,超过常规剂量的12倍。服药后2-12h来诊。1.2诊断标准①有明确误服或超量史;②表现不同程度的中枢神经兴奋或抑制症状;③排除其他原因所致的兴奋、
Compound benzene has piperidine for the treatment of non-infectious diarrhea, improper use of infants and young children can cause poisoning, severe cases can be life-threatening. Our department in the past 10 years received compound benzene poisoning in children with iodine in 31 cases, the application of salvage significant effect, the results are reported as follows. 1 Clinical data 1.1 Case Selection All cases were selected from our hospital emergency and hospitalized children a total of 31 cases, 17 males and 14 females. Age: 11 months in April-1 year old, 9 cases of -2 years old, 8 cases of -3 years old, 3 cases of -5 years old. March 1992 - July 1996 15 cases as a control group (not used naloxone), including 7 males and 8 females, from July 1996 to November 2002 16 cases as a treatment group, of which 10 male Cases, female 6 cases. In all cases, 12 cases were mistakenly taken and 19 cases were orally taken orally. The maximum amount of oral ingestion was 20, more than 12 times of the conventional dosage. 2-12h after treatment. 1.2 diagnostic criteria ① have a clear history of obesity or overdose; ② show varying degrees of central nervous excitement or inhibition of symptoms; ③ exclusion of excitement caused by other reasons,