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报告1例系统性红斑狼疮并发毛母细胞瘤。患者女,40岁。因面部肿块渐大5年余就诊。皮肤科检查:双侧眉弓、眉间、鼻根部、鼻尖及鼻孔周围大片淡红色斑片,略高于皮面,上唇双侧可见3 cm×5 cm褐色斑块,下唇右侧一1.0 cm×1.5 cm红色结节,扁平凸起,表面不光滑,质中,双侧颊部大片黑褐色斑片。皮损组织病理检查:表皮正常,真皮内较多由肿瘤细胞组成的成簇状、条索状,部分成筛孔状结构,累及皮下脂肪组织;肿瘤细胞丰富,似基底样细胞,体积小,嗜碱性,胞质少,中度不典型增生,肿瘤团块周围细胞排列呈栅栏状,可见核分裂象及钙化。诊断:系统性红斑狼疮并发毛母细胞瘤。
One case of systemic lupus erythematosus was reported with hairy cell tumor. Female patient, 40 years old. Due to facial enlargement more than 5 years treatment. Dermatology examination: bilateral eyebrows, eyebrows, nasal root, nasal tip and nostrils around a large patch of reddish patches, slightly higher than the leather, visible on both sides of the upper lip 3 cm × 5 cm brown plaque, a 1.0 cm × 1.5 cm red nodules, flat bulge, the surface is not smooth, medium, large cheeks dark brown patches. Skin lesions histological examination: the normal epidermis, dermis mostly composed of tumor cells clustered, cord-like, part of the mesh-like structure, involving subcutaneous adipose tissue; tumor cells rich, like basal-like cells, small size, Basophilic, less cytoplasm, moderate dysplasia, cells arranged around the tumor were palisading, visible mitosis and calcification. Diagnosis: Systemic lupus erythematosus with hairy cell tumor.