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目的分析扁桃体原发弥漫小圆细胞恶性肿瘤的组织学特点和类型。方法收集该类肿瘤104例,常规HE切片检查和免疫组化检测协助肿瘤来源分析。结果104例中恶性淋巴瘤94例(90.38%),低一未分化癌8例(7.69%),其它2例(1.92%)。复阅该组中8例低一未分化癌的HE切片中,发现尽管瘤细胞主要呈弥漫排列,仍可见到部分区域瘤细胞形态和结构具有癌的特点。对该组94例淋巴瘤进一步分类,结果表明该组扁桃体淋巴瘤类型与一般结内淋巴瘤的类型相似。结论扁桃体原发弥漫小圆细胞恶性肿瘤中未分化癌很少见,绝大多数是恶性淋巴瘤,扁桃体淋巴瘤并无本身的类型特点。
Objective To analyze the histological features and types of tonsil primary diffuse small cell malignant tumor. Methods Totally 104 cases of these tumors were collected, and routine HE-slice and immunohistochemistry were used to assist in the analysis of tumor origin. Results Of 104 cases, 94 (90.38%) had malignant lymphoma, with 8 cases (7.69%) of low undifferentiated carcinoma and 2 cases (1.92%) of the other 2 cases. Review of the group of 8 cases of low-grade undifferentiated carcinoma of the HE section, found that although the tumor cells were diffusely arranged, you can still see part of the regional tumor cell morphology and structure with cancer characteristics. 94 cases of this group of lymphoma further classification, the results show that the type of tonsil lymphoma and general type of node lymphoma similar. Conclusions Undifferentiated carcinoma of primary tonsil diffuse small cell malignant tumor is rare, the vast majority is malignant lymphoma, and tonsil lymphoma does not have its own type characteristics.