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目的 了解围产期窒息对新生儿脑血流 (CBF)的影响及意义。方法 对 1 40例有围产期窒息的新生儿进行单光子发射型计算机断层 (SPECT)脑显像。结果 ①围产期发生的胎儿窘迫或出生时窒息 ,有可能使CBF减少 ;②有胎儿窘迫和 (或 )出生时窒息时 ,新生儿CBF异常的发生率相似。结论 围产期发生了胎儿窘迫或出生时窒息 ,虽经复苏抢救或去除了某些直接影响因素 ,这些新生儿仍然存在着发生缺氧缺血性脑损伤(HIBD)的高度危险。
Objective To investigate the effect and significance of perinatal asphyxia on neonatal cerebral blood flow (CBF). Methods Single photon emission computed tomography (SPECT) brain imaging was performed on 140 neonates with perinatal asphyxia. Results ① Perinatal fetal distress or birth asphyxia, may reduce CBF; ② with fetal distress and (or) birth asphyxia, neonatal CBF abnormalities were similar. Conclusions Fetal distress or birth asphyxia occurred during perinatal period. Although some direct influencing factors were rescued or removed after resuscitation, these neonates still have a high risk of hypoxic-ischemic brain damage (HIBD).