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目的比较传统治疗与血液灌流联合血浆置换对老年重度有机磷中毒的疗效。方法选择在我院接受治疗的50位重度有机磷中毒的老年患者,分为实验组和对照组各525例。实验组采用血液灌流联合血浆置换治疗,对照组采用传统治疗方法。将两组患者与手术前的症状相比较,同时测定相关指标。结果实验组在术前和术后昏迷和呼吸衰竭患者有明显改善,但对照组相对于实验组改善不明显;实验组胆碱酯酶恢复时间、住院时间、中间综合症、死亡数均比对照组低,组间差异有统计学意义(P<0.05)。结论血液灌流联合血浆置换治疗老年重度有机磷中毒较传统治疗方法疗效好。
Objective To compare the curative effect of traditional therapy and hemoperfusion combined with plasma exchange on severe organic phosphorus poisoning in the elderly. Methods Fifty elderly patients with severe organophosphorus poisoning who were treated in our hospital were divided into experimental group and control group with 525 cases each. The experimental group was treated by hemoperfusion combined with plasma exchange, while the control group was treated by traditional method. The two groups of patients with preoperative symptoms compared to determine the relevant indicators. Results The experimental group was significantly improved in patients with preoperative and postoperative coma and respiratory failure, but the control group was not significantly improved compared with the experimental group; the recovery time of cholinesterase, hospital stay, intermediate syndrome and death in the experimental group were significantly higher than those in the control group Group low, the difference between groups was statistically significant (P <0.05). Conclusion Hemoperfusion combined with plasma exchange treatment of severe organic phosphorus poisoning than the traditional treatment method is effective.