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目的:探析利福平与利福喷丁治疗肺结核的临床价值。方法:选择2012年11月-2014年11月期间我县人民医院收治的肺结核住院患者252例作为研究对象,运用随机数字表法将其分为两组,其中给予对照组利福平治疗,而观察组则运用利福喷丁治疗,对两组的治疗效果、空洞闭合率以及痰检阴转率进行对比。结果:两组的治疗总有效率比较差异有统计学意义(P<0.05);同时,相比较对照组而言,观察组的痰检阴转率和空洞闭合率明显较高,组间比较差异有统计学意义。结论:在肺结核的治疗中,与利福平相比,利福喷丁具有安全性好、疗效好、不良反应少等诸多优点,是比较有效的一种药物。
Objective: To investigate the clinical value of rifampin and rifapentine in the treatment of pulmonary tuberculosis. Methods: A total of 252 hospitalized cases of tuberculosis admitted to our county People’s Hospital from November 2012 to November 2014 were selected as research objects. Random number table was used to divide them into two groups, which were treated with rifampicin in control group. The observation group was treated with rifapentine, the treatment effect of the two groups, empty closure rate and sputum test negative conversion rate compared. Results: The total effective rate of the two groups was statistically significant difference (P <0.05); at the same time, compared with the control group, the observation group sputum examination negative conversion rate and void closure rate was significantly higher, the difference between groups There is statistical significance. Conclusion: In the treatment of tuberculosis, compared with rifampicin, rifapentine has many advantages such as good safety, good curative effect and few adverse reactions. It is a more effective drug.