在急、慢性肝脏疾病中,有相当一部分被称为“自发性”、“原发性”或“隐原性”肝病,这都说明其病因不明。最近的流行病学研究提示,有些病因不明的肝脏疾病可能是由于职业性接触化学物所致。职业性肝损根据其不同的致病因素可分为三个主要类型:感染性、物理性和化学性。这种分类只提及单因素的职业性肝损,实际情况则要复杂得多,如使用口服避孕药 In acute and chronic liver disease, a considerable portion is called “spontaneous”, “primary” or “cryptogenic” liver disease, all of which indicate that the etiology is unknown. Recent epidemiological studies suggest that some liver diseases of unknown etiology may be caused by occupational exposure to chemicals. Occupational liver damage according to their different risk factors can be divided into three main types: infectious, physical and chemical. This classification refers only to single-factor occupational liver damage, the actual situation is much more complex, such as the use of oral contraceptives