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血液透析时血压的不稳定性虽早有认识,但对造成透析时非系统性血压变异性的因素知之甚少。方法:进行前瞻性观察队列研究。研究对象是来自5个透析中心接受普通透析的随机患者218例。测量可能影响收缩压变异性的临床变量。观察指标:收缩压变异性,定义为与预期收缩压变化值的差距(主要指标),以及收缩压连续测量值差异的绝对值(次要指标)。
Although hemodialysis blood pressure instability has long been recognized, but caused by dialysis non-systematic variability of blood pressure is poorly understood. Methods: A prospective observational cohort study was conducted. The study population consisted of 218 randomized patients from five dialysis centers undergoing universal dialysis. Clinical variables that may affect the variability of systolic blood pressure are measured. Observations: Systolic blood pressure variability, defined as the difference from expected changes in systolic blood pressure (the primary indicator), and the absolute value of secondary differences in systolic blood pressure measurements.