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132例高脂血症患者口服薤白提取物胶丸4周后,比较服药前后血浆总胆固醇、β脂蛋白、血浆6-酮-前列腺素 F_(1α)的变化,P 值均<0.001;血小板聚集率服药前后对比 P<0.01,表明该药有降低血脂、提高6-酮-前列腺素 F_(1α)水平、抑制血小板聚集的作用,为防治动脉粥样硬化提供了一个有效的新型药物。
132 patients with hyperlipidemia were treated with Oral White Extract capsules for 4 weeks. Changes in plasma total cholesterol, β-lipoprotein, and plasma 6-keto-prostaglandin F_(1α) were observed before and after administration. The P value was less than 0.001; platelet aggregation was observed. The ratio of P<0.01 before and after administration of the drug indicates that the drug has the functions of lowering blood lipid, increasing 6-keto-prostaglandin F1(1α) level, inhibiting platelet aggregation, and providing an effective new drug for preventing and treating atherosclerosis.